Contents, introduction edit, prednisone, prednisone is a drug that belongs to the class of corticosteroids which is a steroid. Steroids are prednisone acetate ophthalmic suspension usp hormones with similar chemical structure that gather together as a group. In prednisone acetate ophthalmic suspension usp general, Prednisone prednisone prednisone acetate ophthalmic suspension usp for cough is produced by your adrenal gland which is located on top of kidneys. It prednisone for cough is used to treat people who have low levels of corticosteroids. It works in prednisone for cough preventing the flammable substances in the body. Patients with the following conditions can be treated with. Prednisone prednisone for cough : skin conditions, lupus, arthritis, breathing disorder, or allergic disorder at regular doses, or it can be treated with cancer at higher doses. This drug is no t highly recommended since it has really severe side effects. History and Usage edit, arthur Nobile was the one who identified the structure. Not until 1955, Prednisone synthesis was carried out in the laboratory of Schering Corporation; it is a replica of cortisone- which is produced by the outer portion of the adrenal glands. Nowadays, Prednisone can be prescribed as generic drugs. Prednisone comes as a tablet so it can be taken directly by mouth. You should eat something first before taking this drug. You should be taking at direct dose as prescribed because it can cause serious side effects if prednisone acetate ophthalmic suspension usp you overdose. Your doctor will adjust your dose while you follow up with the treatment- but mostly the lowest dose that your body can take. Do not stop using Prednisone even if you feel better because your body might not have enough steroids that come from this drug to function normally. Mechanism edit, prednisone is a glucocorticoid receptor. It will first be metabolize to its active form and come across the cell membrane and attach to specific cytoplasmic receptors. This results in leukocyte infiltration of inflammation, interference of inflammatory response, and suppression of immune response. The anti-inflammatory and immunosuppressive actions which is a mechanism of prednisone can be described as followed: Inhibition of gene transcription, blockage of osteocalcin, changing prednisone for cough in transcription of collegenase gene. Increase the synthesis of annexin-1, side Effects edit, prednisone. You should remember that, prednisone is a type of steroid. It is a really powerful drug that can save life if it is used properly. Just as many other prednisone for cough drugs, it also has side effects that can be really harmful. Some common minor side effects that you might experience while using this drug are: Headache, dizziness, sleeping disorder. Skin allergy, extreme tiredness, weak muscle, other people might face severe side effects that needs to be taken with cautions and notify your doctor immediately. Vision problem, sore throat, fever, hacking cough, rash. Stomach pain, vomiting, depression, confusion Breathing disorder References prednisone acetate ophthalmic suspension usp edit ml prednisone acetate ophthalmic suspension usp ml ahfs Consumer Medication Information- Prednisone.
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Dosage Form: tablets; oral solution; oral solution, concentrate. Show On This Page, view All, show On This Page. Rx only, prednisone Description, prednisone Tablets USP are available for 5mg prednisone oral administration containing either 1 mg,.5 mg, 5mg prednisone 5 mg, 10 mg, 20 mg or 50 mg of Prednisone USP. Each tablet contains the following inactive ingredients: lactose monohydrate, magnesium stearate, microcrystalline cellulose, pregelatinized starch, sodium starch glycolate and stearic acid (1 mg,.5 mg, and 5 mg only). Prednisone Oral Solution USP is formulated for oral administration containing 5 mg per 5 mL of Prednisone USP and alcohol. The oral solution contains the following inactive ingredients: anhydrous citric acid, edetate disodium, 5mg prednisone fructose, hydrochloric acid, maltol, peppermint oil, polysorbate 80, propylene glycol, saccharin sodium, sodium benzoate, vanilla flavor and purified water. Prednisone Intensol Oral Solution (Concentrate) is formulated for oral administration containing 5 mg per mL of Prednisone USP and alcohol. In addition, the oral solution contains the following inactive ingredients: anhydrous citric acid, poloxamer 188, propylene glycol and purified water. Prednisone tablets contain Prednisone which is a glucocorticoid. Glucocorticoids are adrenocortical steroids, both naturally occurring and synthetic, which are readily absorbed from the gastrointestinal tract. The chemical name for Prednisone is The structural formula is represented below: C21H26O5.W. 358.44, prednisone is a white to partially white, crystalline powder. It is very slightly soluble in water; slightly soluble in alcohol, chloroform, dioxane, and methanol. Prednisone - Clinical Pharmacology. Naturally occurring glucocorticoids (hydrocortisone and cortisone which also have salt-retaining properties, are used as replacement therapy in adrenocortical deficiency states. Their synthetic analogs are primarily used for their potent anti-inflammatory effects in disorders of many organ systems. Glucocorticoids cause profound and varied metabolic effects. In addition, they modify the bodys immune responses to diverse stimuli. Indications and Usage for Prednisone, prednisone tablets and solutions are indicated in the following conditions: Endocrine Disorders, 5mg prednisone primary or secondary adrenocortical insufficiency (hydrocortisone or cortisone is the first choice: synthetic analogs may be used in conjunction with mineralocorticoids where applicable; in infancy mineralocorticoid supplementation. As adjunctive therapy for short-term administration (to tide the patient over an acute episode or exacerbation) in: psoriatic arthritis, rheumatoid arthritis, including juvenile rheumatoid arthritis (selected cases may require low-dose maintenance therapy ankylosing spondylitis, acute and subacute bursitis, acute nonspecific tenosynovitis, acute gouty arthritis, post-traumatic. Collagen Diseases, during an exacerbation or as maintenance therapy in selected cases of: systemic lupus erythematosus, systemic dermatomyositis (polymyositis acute rheumatic carditis. Dermatologic Diseases, pemphigus; bullous dermatitis herpetiformis; severe erythema multiforme (Stevens-Johnson syndrome exfoliative dermatitis; mycosis fungoides; severe psoriasis; severe seborrheic dermatitis. Allergic States, control of severe or incapacitating allergic conditions intractable to adequate trials of conventional treatment: seasonal or perennial allergic rhinitis; bronchial asthma; contact dermatitis; atopic dermatitis; serum sickness; drug hypersensitivity reactions. Severe acute and chronic allergic and inflammatory processes involving the eye and its adnexa such as: allergic corneal marginal ulcers, herpes zoster ophthalmicus, anterior segment inflammation, diffuse posterior uveitis and choroiditis, sympathetic ophthalmia, allergic conjunctivitis, keratitis, chorioretinitis, optic neuritis, iritis and iridocyclitis. Respiratory Diseases, symptomatic sarcoidosis; Loefflers syndrome not manageable by other means; berylliosis; fulminating or disseminated pulmonary tuberculosis when used concurrently with appropriate antituberculous chemotherapy; aspiration pneumonitis. Hematologic Disorders, idiopathic thrombocytopenic purpura in adults; secondary thrombocytopenia in adults; acquired (autoimmune) hemolytic anemia; erythroblastopenia (RBC anemia congenital (erythroid) hypoplastic anemia. Neoplastic Diseases, for palliative management of: leukemias and lymphomas in adults, acute leukemia of childhood. To induce a diuresis or remission of proteinuria in the nephrotic syndrome, without uremia, of the idiopathic type or that due to lupus erythematosus. Gastrointestinal Diseases, to tide the patient over a critical period of the disease in: ulcerative colitis, regional enteritis. Miscellaneous, tuberculous meningitis with subarachnoid block or impending block when used concurrently with appropriate antituberculous chemotherapy; trichinosis 5mg prednisone with neurologic or myocardial involvement.